MitrevaLab specializes in advancing our understanding of infectious diseases and microbiome dynamics through cutting-edge genomic and computational approaches. Under the leadership of Dr. Makedonka Mitreva, the lab integrates multi-omics data analysis, machine learning, and experimental validation to study host-pathogen interactions, particularly in neglected tropical diseases and helminth infections. Their research extends to investigating the complex relationships between human microbiomes and disease states, contributing to the development of novel therapeutic strategies and improved diagnostic tools.
Neglected Tropical Diseases
At the Mitreva Lab we employ cutting-edge genomic and computational approaches to combat neglected tropical diseases (NTDs), particularly parasitic helminths such as hookworms and whipworms. These parasites afflict over a billion people globally, leading to severe health issues like blindness, anemia, and developmental delays, especially in low-resource communities. By integrating systems biology, multi-omics data analysis, and machine learning, the lab aims to uncover molecular mechanisms of infection and drug resistance, facilitating the development of targeted therapies and advancing global health initiatives.
Human Microbiome
The Mitreva Lab is at the forefront of human microbiome research, exploring the complex communities of microorganisms residing in the human body. Dr. Mitreva played a pivotal role in the NIH-funded Human Microbiome Project, leading the Shotgun Metagenomics Working Group. Her team continues to investigate how microbial communities influence health and disease, utilizing multi-omics analyses and computational tools to identify microbial functions and members associated with various conditions. This research is instrumental in developing microbiome-based diagnostics and therapies, paving the way for personalized medicine.
Join the Team!
By joining Mitreva Lab you will become a member of a highly interdisciplinary team, and will have opportunities to contribute to ongoing projects and design new ones within the framework of our broad research portfolio.
Latest News
Intestinal cell diversity and treatment responses in a parasitic nematode at single cell resolution
Congratulations to the eLABE group for this fantastic publication!
