I enjoy working with trainees, staff, and collaborators to advance projects that will yield new information about neuronal communication and that will spur insight into health and disease.
I’m studying the role of GABA receptors containing the δ subunit in drug effects and in physiological inhibition.
I participate in virtually all projects by managing the lab, preparing cultures, performing surgeries, and imaging specimens.
I examine the effect of different culture substrates on neuronal development. I develope image analysis approaches to quantify dendritic complexity.
My main interests are in neurosteroid modulation of GABA receptors. I’m also exploring the transcription changes in neurons to various environmental and genetic changes.
I’m analyzing the transcriptional changes that accompany local contact between astrocytes and neurons.
I am currently investigating the mechanisms by which neurosteroids are trafficked through neurons and developing novel chemical probes to study the modulation of NMDA receptors.