Publications

Pubmed

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  1. Maloney SE, Sarafinovska S, Weichselbaum C, McCullough KB, Swift RG, Liu Y, Dougherty JD. A comprehensive assay of social motivation reveals sex-specific roles of autism-associated genes and oxytocin. Cell Rep Methods. 2023 Jun 16;3(6):100504. doi: 10.1016/j.crmeth.2023.100504. PMID: 37426756; PMCID: PMC10326376.
  2. Nygaard KR, Maloney SE, Swift RG, McCullough KB, Wagner RE, Fass SB, Garbett K, Mirnics K, Veenstra-VanderWeele J, Dougherty JD. Extensive characterization of a Williams syndrome murine model shows Gtf2ird1-mediated rescue of select sensorimotor tasks, but no effect on enhanced social behavior. Genes Brain Behav. 2023 Jun 27:e12853. doi: 10.1111/gbb.12853. Epub ahead of print. PMID: 37370259.
  3. Minakova E, Mikati MO, Madasu MK, Conway SM, Baldwin JW, Swift RG, McCullough KB, Dougherty JD, Maloney SE*, Al-Hasani R*. Perinatal oxycodone exposure causes long-term sex-dependent changes in weight trajectory and sensory processing in adult mice. Psychopharmacology (Berl). 2022 Dec;239(12):3859-3873. doi: 10.1007/s00213-022-06257-8. Epub 2022 Oct 21. PubMed PMID: 36269379.   *dual senior authorship
  4. Maloney SE, Tabachnick DR, Jakes C, Avdagic S, Bauernfeind AL, Dougherty JD. Fluoxetine exposure throughout neurodevelopment differentially influences basilar dendritic morphology in the motor and prefrontal cortices. Sci Rep. 2022 May 9;12(1):7605. doi: 10.1038/s41598-022-11614-w. PubMed PMID: 35534532; PubMed Central PMCID: PMC9085735.
  5. Weston KP, Gao X, Zhao J, Kim KS, Maloney SE, Gotoff J, Parikh S, Leu YC, Wu KP, Shinawi M, Steimel JP, Harrison JS, Yi JJ. Identification of disease-linked hyperactivating mutations in UBE3A through large-scale functional variant analysis. Nat Commun. 2021 Nov 23;12(1):6809. doi: 10.1038/s41467-021-27156-0. PubMed PMID: 34815418; PubMed Central PMCID: PMC8635412
  6. Chen J, Lambo ME, Ge X, Dearborn JT, Liu Y, McCullough KB, Swift RG, Tabachnick DR, Tian L, Noguchi K, Garbow JR, Constantino JN, Gabel HW, Hengen KB, Maloney SE*, Dougherty JD*. A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation. Neuron. 2021 Dec 1;109(23):3775-3792.e14. doi: 10.1016/j.neuron.2021.09.009. Epub 2021 Oct 5. PubMed PMID: 34614421; PubMed Central PMCID: PMC8668036. *dual senior authorship
  7. Meganathan K, Prakasam R, Baldridge D, Gontarz P, Zhang B, Urano F, Bonni A, Maloney SE, Turner TN, Huettner JE, Constantino JN, Kroll KL. Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7. BMC Biol. 2021 Jul 28;19(1):147. doi: 10.1186/s12915-021-01080-7. PubMed PMID: 34320968; PubMed Central PMCID: PMC8317352.
  8. Nygaard, K.R., Swift, R.G., Glick, R.M., Wagner, R.E., Maloney, SE, Gould, G.G., and Dougherty, J.D. Oxytocin receptor activation does not mediate associative fear deficits in a Williams Syndrome model. Genes Brain Behav. 2021 May 12;:e12750. doi: 10.1111/gbb.12750. [Epub ahead of print] PubMed PMID: 33978321.
  9. Rahn RM, Weichselbaum CT, Gutmann DH, Dougherty JD, Maloney SE. (2021) Shared developmental gait disruptions across two mouse models of neurodevelopmental disorders. J Neurodev Disord. 2021 Mar 20;13(1):10. doi: 10.1186/s11689-021-09359-0. PubMed PMID: 33743598; PubMed Central PMCID: PMC7980331.
  10. Sakers K, Liu Y, Llaci L, Vasek MJ, Rieger MA, Brophy S, Tycksen E, Lewis R, Maloney SE, Dougherty JD. CRISPR-TRAPSeq identifies the QKI RNA binding protein as important for astrocytic maturation and control of thalamocortical synapses. Nat Commun. 2021 Mar 9;12(1):1537. doi: 10.1038/s41467-021-21703-5. PubMed PMID: 33750804; PubMed Central PMCID: PMC7943582.
  11. Minakova E, Sarafinovska S, Mikati MO, Barclay KM, McCullough KB, Dougherty JD, Al-Hasani R, Maloney SE. Ontogenetic Oxycodone Exposure Affects Early Life Communicative Behaviors, Sensorimotor Reflexes, and Weight Trajectory in Mice. Front Behav Neurosci. 2021;15:615798. doi: 10.3389/fnbeh.2021.615798. eCollection 2021. PubMed PMID: 33692675; PubMed Central PMCID: PMC7937712.
  12. Palanisamy A, Giri T, Jiang J, Bice A, Quirk JD, Conyers SB, Maloney SE, Raghuraman N, Bauer AQ, Garbow JR, Wozniak DF. In utero exposure to transient ischemia-hypoxemia promotes long-term neurodevelopmental abnormalities in male rat offspring. JCI Insight. 2020 May 21;5(10). doi: 10.1172/jci.insight.133172. PubMed PMID: 32434985; PubMed Central PMCID: PMC7259513.
  13. Kopp ND, Nygaard KR, Liu Y, McCullough KB, Maloney SE, Gabel HW, Dougherty JD. Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences. Hum Mol Genet. 2020 Jun 3;29(9):1498-1519. doi: 10.1093/hmg/ddaa070. PubMed PMID: 32313931; PubMed Central PMCID: PMC7526791.
  14. Akula SK, McCullough KB, Weichselbaum C, Dougherty JD, Maloney SE. The trajectory of gait development in mice. Brain Behav. 2020 Jun;10(6):e01636. doi: 10.1002/brb3.1636. Epub 2020 Apr 24. PubMed PMID: 32333523; PubMed Central PMCID: PMC7303394.
  15. Cammack AJ, Moudgil A, Chen J, Vasek MJ, Shabsovich M, McCullough K, Yen Al, Lagunas T, Maloney SE, He J, Chen X, Hooda M, Wilkinson MN, Miller TM, Mitra RD, Dougherty JD. A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues. PNAS, 2020 117(18):1000.-10014. PMID: 32300008
  16. Rahn RM, Maloney SE, Brier LM, Dougherty JD, Culver JP. Maternal Fluoxetine Exposure Alters Cortical Hemodynamic and Calcium Response of Offspring to Somatosensory Stimuli. eNeuro. 2019 Nov/Dec;6(6). doi: 10.1523/ENEURO.0238-19.2019. Print 2019 Nov/Dec. PubMed PMID: 31843753; PubMed Central PMCID: PMC6978917
  17. Kopp ND, McCullough K, Maloney SE, Dougherty JD. Gtf2i and Gtf2ird1 mutation are not sufficient to reproduce mouse phenotypes caused by the Williams Syndrome critical region. Human Molecular Genetics. 2019 Oct; 28(20):3443-3465, PMID: 31418010
  18. Maloney SE, Rieger MA, Al-Hasani R, Bruchas MR, Wozniak DF, Dougherty JD. Loss of CELF6 RNA binding protein impairs cocaine conditioned place preference and contextual fear conditioning. Genes Brain Behav. 2019 Sep;18(7):e12593. doi: 10.1111/gbb.12593. Epub 2019 Jun 19. PubMed PMID: 31215739.
  19. Nygaard KR, Maloney SE, Dougherty JD. Erroneous inference based on a lack of preference within one group: Autism, mice, and the social approach task. Autism Res. 2019 Aug;12(8):1171-1183. doi: 10.1002/aur.2154. Epub 2019 Jun 11. PubMed PMID: 31187603; PubMed Central PMCID: PMC6688965.
  20. Maloney SE, Yuede CM, Creeley CE, Williams SL, Huffman JN, Taylor GT, Noguchi KN, Wozniak DF. Repeated neonatal isoflurane exposures in the mouse induce apoptotic degenerative changes in the brain and relatively mild long-term behavioral deficits. Sci Rep. 2019 Feb 26;9(1):2779. doi: 10.1038/s41598-019-39174-6. PubMed PMID: 30808927; PubMed Central PMCID: PMC6391407.
  21. Cheng C, Deng PY, Ikeuchi Y, Yuede C, Li D, Rensing N, Huang J, Baldridge D, Maloney SE, Dougherty JD, Constantino J, Jahani-Asl A, Wong M, Wozniak DF, Wang T, Klyachko VA, Bonni A. Characterization of a Mouse Model of Börjeson-Forssman-Lehmann Syndrome. Cell Rep. 2018 Nov 6;25(6):1404-1414.e6. doi: 10.1016/j.celrep.2018.10.043. PubMed PMID: 30403997; PubMed Central PMCID: PMC6261530
  22. Maloney SE, Akula S, Rieger MA, McCullough KB, Chandler K, Corbett AM, McGowin AE, Dougherty JD: Examining the Reversibility of Long-Term Behavioral Disruptions in Progeny of Maternal SSRI Exposure. eNeuro 2018;5(4) PMID: 30073191; PMC6071194.
  23. McGill BE, Barve RA, Maloney SE, Strickland A, Rensing N, Wang PL, Wong M, Head R, Wozniak DF, Milbrandt J: Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion of Ctcf in Camk2a-Cre-Expressing Neurons. J Neurosci. 2018;38(1):200-219. PubMed PMID: 29133437; PubMed Central PMCID: PMC5761433.

Susan’s work pre-dating the lab:

  1. Maloney SE, Chandler KC, Anastasaki C, Rieger MA, Gutmann DH, Dougherty JD: Characterization of early communicative behavior in mouse models of neurofibromatosis type 1. Autism Res. 2018;11(1):44-58. PubMed PMID: 28842941; NIHMSID: NIHMS914406; PubMed Central PMCID: PMC5773379.
  2. Maloney SE, Khangura E, Dougherty JD. The RNA-binding protein Celf6 is highly expressed in diencephalic nuclei and neuromodulatory cell populations of the mouse brain. Brain Struct Funct. 2016;221(4):1809-1831. PubMed PMID: 25682262; NIHMSID: NIHMS685069; PubMed Central PMCID: PMC4537696.
  3. Yanamandra K, Jiang H, Mahan TE, Maloney SE, Wozniak DF, Diamond MI, Holtzman DM: Anti-tau antibody reduces insoluble tau and decreases brain atrophy. Ann Clin Transl Neurol. 2015;2(3):278-288. PubMed PMID: 25815354; PubMed Central PMCID: PMC4369277.
  4. Yanamandra K, Kfoury N, Jiang H, Mahan TE, Ma S, Maloney SE, Wozniak DF, Diamond MI, Holtzman DM: Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo. Neuron. 2013;80(2):402-414. PubMed PMID: 24075978; NIHMSID: NIHMS548975; PubMed Central PMCID: PMC3924573.
  5. DeVos SL, Goncharoff DK, Chen G, Kebodeaux CS, Yamada K, Stewart FR, Schuler DR, Maloney SE, Wozniak DF, Rigo F, Bennett CF, Cirrito JR, Holtzman DM, Miller TM: Antisense reduction of tau in adult mice protects against seizures. J Neurosci. 2013;33(31):12887-12897. PubMed PMID: 23904623; PubMed Central PMCID: PMC3728694.
  6. Reno CM, Tanoli T, Bree A, Daphna-Iken D, Cui C, Maloney SE, Wozniak DF, Fisher SJ: Antecedent glycemic control reduces severe hypoglycemia-induced neuronal damage in diabetic rats. Am J Physiol Endocrinol Metab. 2013;304(12):E1331-E1337. PubMed PMID: 23592483; PubMed Central PMCID: PMC3680694.
  7. Dalal J, Roh JH, Maloney SE, Akuffo A, Shah S, Yuan H, Wamsley B, Jones WB, de Guzman Strong C, Gray PA, Holtzman DM, Heintz N, Dougherty JD: Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation. Genes Dev. 2013;27(5):565-578. PubMed PMID: 23431030; PubMed Central PMCID: PMC3605469.
  8. Dougherty JD, Maloney SE, Wozniak DF, Rieger MA, Sonnenblick L, Coppola G, Mahieu NG, Zhang J, Cai J, Patti GJ, Abrahams BS, Geschwind DH, Heintz N: The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. J Neurosci. 2013;33(7):2732-2753. PubMed PMID: 23407934; NIHMSID: NIHMS445869; PubMed Central PMCID: PMC3711589.
  9. Taylor GT, Dearborn JT, Maloney SE. Adrenal steroids uniquely influence sexual motivation behavior in male rats. Behav Sci (Basel). 2012;2(3):195-206. PubMed PMID: 25379221; PubMed Central PMCID: PMC4217631.
  10. Maloney SE, Noguchi KK, Wozniak DF, Fowler SC, Farber NB. Long-term Effects of Multiple Glucocorticoid Exposures in Neonatal Mice. Behav Sci (Basel). 2011 Dec 30;1(1):4-30. PubMed PMID: 22375274; NIHMSID: NIHMS348363; PubMed Central PMCID: PMC3286606.
  11. Thio LL, Rensing N, Maloney S, Wozniak DF, Xiong C, Yamada KA: A ketogenic diet does not impair rat behavior or long-term potentiation. Epilepsia. 2010;51(8):1619-1623. PubMed PMID: 20132289; NIHMSID: NIHMS246502; PubMed Central PMCID: PMC2996229.
  12. Taylor GT, Maloney S. Gender differences and the role of estrogen in cognitive enhancements with nicotine in rats. Pharmacol Biochem Behav. 2010;95(2):139-145. PubMed PMID: 20074585.
  13. Puente EC, Silverstein J, Bree AJ, Musikantow DR, Wozniak DF, Maloney S, Daphna-Iken D, Fisher SJ: Recurrent moderate hypoglycemia ameliorates brain damage and cognitive dysfunction induced by severe hypoglycemia. Diabetes. 2010 Apr;59(4):1055-1062. PubMed PMID: 20086229; PubMed Central PMCID: PMC2844814.