2023
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function (Links to an external site)
Haoui M, Vergara C, and Lishko PV
In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes (Links to an external site)
Chen Z, Greenan GA, Shiozaki M, Liu Y, Skinner WM, Zhao X, Zhao S, Yan R, Yu Z, Lishko PV, Agard DA, Vale RD
2022
Human sperm TMEM95 binds eggs and facilitates membrane fusion (Links to an external site)
Tang S, Lu Y, Skinner WM, Sanyal M, Lishko PV, Ikawa M, Kim PS
Mitochondrial uncouplers impair human sperm motility without altering ATP content (Links to an external site)
Skinner WM, Petersen NT, Unger B, Tang S, Tabarsi E, Lamm J, Jalalian L, Smith J, Bertholet AM, Xu K, Kirichok Y, and Lishko PV
Editorial: Endocrine and paracrine regulation of spermatogenesis (Links to an external site)
Goldberg E, Lishko PV, Papadopoulos V, Zirkin B
3D structure and in situ arrangements of CatSper channel in the sperm flagellum (Links to an external site)
Zhao Y, Wang H, Wiesehoefer C, Shah NB, Reetz E, Hwang JY, Huang X, Wang TE, Lishko PV, Davies KM, Wennemuth G, Nicastro D, Chung JJ
2021
Alpha/Beta Hydrolase Domain-Containing Protein 2 Regulates the Rhythm of Follicular Maturation and Estrous Stages of the Female Reproductive Cycle (Links to an external site)
Björkgren I, Chung DH, Mendoza S, Gabelev-Khasin L, Petersen NT, Modzelewski A, He L, and Lishko Polina V
The epithelial potassium channel Kir7.1 is stimulated by progesterone (Links to an external site)
Björkgren I, Mendoza S, Chung DH, Haoui M, Petersen NT, and Lishko PV
Choroid plexus epithelial cells as a model to study nongenomic steroid signaling and its effect on ion channel function (Links to an external site)
Haoui M, Petersen NT, Björkgren Ida, Chung DH, and Lishko PV
Recording Electrical Currents across the Plasma Membrane of Mammalian Sperm Cells (Links to an external site)
Liu B, Mundt N, Miller M, Clapham DE, Kirichok Y, and Lishko PV
The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility (Links to an external site)
Gabelev KL, Della RJ, Petersen N, Moeller J, Kriegsfeld LJ, and Lishko PV
Dissecting the signaling pathways involved in the function of sperm flagellum (Links to an external site)
Vyklicka L, and Lishko PV
Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility (Links to an external site)
Hwang JY, Mannowetz N, Zhang Y, Everley RA, Gygi SP, Bewersdof J, Lishko PV, and Chung JJ
Single-cell Motility Analysis of Tethered Human Spermatozoa (Links to an external site)
Skinner WM, Mannowetz N, Lishko PV, and Roan NR
Single-cell Motility Analysis of Tethered Human Spermatozoa (Links to an external site)
Skinner WM, Mannowetz N, Lishko PV, and Roan NR
Asymmetrically Positioned Flagellar Control Units Regulate Human Sperm Rotation (Links to an external site)
Miller M, Kenny S, Mannowetz N, Mansell S, Wojcik M, Mendoza S, Zucker R, Xu K, and Lishko PV
TRPV4 is the temperature-sensitive ion channel of human sperm (Links to an external site)
Mundt N, Spehr M, and Lishko PV
Semen amyloids participate in spermatozoa selection and clearance (Links to an external site)
Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Standker L, Rocker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O’Rand M, Lishko PV, Kirchhoff F, Munch J, and Greene WC
Regulation of the sperm calcium channel CatSper by steroids (Links to an external site)
Mannowetz N, Miller MR, and Lishko PV
Contraception: Search for an Ideal Unisex Mechanism by Targeting Ion Channels (Links to an external site)
Lishko PV
Signaling the differences between cilia (Links to an external site)
Lishko PV, and Kirichok Y
The Fungal Sexual Pheromone Sirenin Activates the Human CatSper Channel Complex (Links to an external site)
Syeda SS, Carlson EJ, Miller MR, Francis R, Clapham DE, Lishko PV, Hawkinson JE, Hook D, and Georg GI
Progesterone Accelerates the Completion of Sperm Capacitation and Activates CatSper Channel in Spermatozoa from the Rhesus Macaque (Links to an external site)
Sumigama S, Mansell S, Miller M, Lishko PV, Cherr GN, Meyers SA, and Tollner T
Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa (Links to an external site)
Williams HL, Mansell S, Alasmari W, Brown SG, Wilson SM, Sutton KA, Miller MR, Lishko PV, Barratt CL, Publicover SJ, and Martins da Silva S
miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110 (Links to an external site)
Song R, Walentek P, Sponer N, Klimke A, Lee JS, Dixon G, Harland R, Wan Y, Lishko PV, Muriel L, Kessel M, and He L
Sperm patch-clamp (Links to an external site)
Lishko PBV, Clapham DE, Navaro B, and Kirichok Y
Slo1 is the principal potassium channel of human spermatozoa (Links to an external site)
Mannowetz N, Naidoo NM, Choo SS, Smith JF, and Lishko PV
Disruption of the principal, progesterone-activated sperm Ca2+ channel in a CatSper2-deficient infertile patient (Links to an external site)
Smith JF, Syritsyna O, Fellous M, Serres C, Mannowetz N, Kirichok Y, and Lishko PV
The Mechanism of UCP1-dependent Thermogenic Uncoupling in Brown Fat Mitochondria (Links to an external site)
Fedorenko A, Lishko PV, and Kirichok Y
Three-Dimensional Structure of the Bovine Sperm Connecting Piece Revealed by Electron Cryotomography (Links to an external site)
Ounjai P, Kim K, Lishko PV, and Downing KH
The role of hv1 and CatSper channels in sperm activation (Links to an external site)
Lishko PV, and Kirichok Y
Acid extrusion from human spermatozoa is mediated by flagellar voltage-gated proton channel (Links to an external site)
Lishko PV, Botchkina IL, Fedorenko A, and Kirichok Y
Functional comparison of RGS9 splice isoforms in a living cell (Links to an external site)
Martemyanov KA, Krispel CM, Lishko PV, Burns ME, and Arshavsky VY
Structural analyses of the ankyrin repeat domain of TRPV6 and related TRPV ion channels (Links to an external site)
Phelps CB, Huang RJ, Lishko PV, Wang RR, and Gaudet R
Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels (Links to an external site)
Phelps CB, Procko E, Lishko PV, Wang RR, and Gaudet R
The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity (Links to an external site)
Lishko PV, Procko E, Jin X, Phelps CB, and Gaudet R
Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors (Links to an external site)
Strissel KJ, Lishko PV, Trieu LH, Kennedy MJ, Hurley JB, and Arshavsky VY
Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors (Links to an external site)
Strissel KJ, Lishko PV, Trieu LH, Kennedy MJ, Hurley JB, and Arshavsky VY
The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo (Links to an external site)
Martemyanov KA, Lishko PV, Calero N, Keresztes G, Sokolov M, Strissel KJ, Leskov IB, Hopp JA, Kolesnikov AV, Chen C-K, Lem J, Heller S, Burns ME, and Arshavsky VY
Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activity (Links to an external site)
Lishko PV, Martemyanov KA, Hopp JA, Arshavsky VY
BN52021, a platelet activating factor antagonist, is a selective blocker of glycine-gated chloride channel (Links to an external site)
Kondratskaya EL, Lishko PV, Chatterjee SS, and Krishtal O
A new class of agonists and antagonists of N-methyl-D-aspartic acid receptors: Derivatives of imidazole-4,5- and pyrazole-3,4-dicarboxylic acids (Links to an external site)
Piotrovskii LB, Lishko PV, Maksimyuk AP, Alexsandrova IY, and Kryshtal OA