Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice.
Gonzalez-Perez V, Martinez-Espinosa PL, Sala-Rabanal M, Bharadwaj N, Xia XM, Chen AC, Alvarado D, Gustafsson JK, Hu H, Ciorba MA, Lingle CJ.
Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2019149118. doi: 10.1073/pnas.2019149118. PMID: 33431687
ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9.
Smeland MF, McClenaghan C, Roessler HI, Savelberg S, Hansen G?M, Hjellnes H, Arntzen KA, Müller KI, Dybesland AR, Harter T, Sala-Rabanal M, Emfinger CH, Huang Y, Singareddy SS, Gunn J, Wozniak DF, Kovacs A, Massink M, Tessadori F, Kamel SM, Bakkers J, Remedi MS, Van Ghelue M, Nichols CG, van Haaften G.
Nat Commun. 2019 Oct 1;10(1):4457. doi: 10.1038/s41467-019-12428-7.
PMID: 31575858
Intestinal absorption of glucose in mice as determined by positron emission tomography.
Sala-Rabanal M, Ghezzi C, Hirayama BA, Kepe V, Liu J, Barrio JR, Wright EM.
J Physiol. 2018 Jul;596(13):2473-2489. doi: 10.1113/JP275934. Epub 2018 Jun 5. PMID: 29707805
Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Deng Z, Paknejad N, Maksaev G, Sala-Rabanal M, Nichols CG, Hite RK, Yuan P.
Nat Struct Mol Biol. 2018 Mar;25(3):252-260. doi: 10.1038/s41594-018-0037-5. Epub 2018 Feb 26. PMID: 29483651
Cantu syndrome-associated SUR2 (ABCC9) mutations in distinct structural domains result in KATP channel gain-of-function by differential mechanisms.
McClenaghan C, Hanson A, Sala-Rabanal M, Roessler HI, Josifova D, Grange DK, van Haaften G, Nichols CG.
J Biol Chem. 2018 Feb 9;293(6):2041-2052. doi: 10.1074/jbc.RA117.000351. Epub 2017 Dec 22. PMID: 29275331
Modulation of TMEM16A channel activity by the von Willebrand factor type A (VWA) domain of the calcium-activated chloride channel regulator 1 (CLCA1).
Sala-Rabanal M, Yurtsever Z, Berry KN, Nichols CG, Brett TJ.
J Biol Chem. 2017 Jun 2;292(22):9164-9174. doi: 10.1074/jbc.M117.788232. Epub 2017 Apr 18. PMID: 28420732
Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption.
Jimah JR, Salinas ND, Sala-Rabanal M, Jones NG, Sibley LD, Nichols CG, Schlesinger PH, Tolia NH.
Elife. 2016 Dec 1;5:e20621. doi: 10.7554/eLife.20621. PMID: 27906127
Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice.
Sala-Rabanal M, Hirayama BA, Ghezzi C, Liu J, Huang SC, Kepe V, Koepsell H, Yu A, Powell DR, Thorens B, Wright EM, Barrio JR.
J Physiol. 2016 Aug 1;594(15):4425-38. doi: 10.1113/JP271904. Epub 2016 May 10. PMID: 27018980
Differential mechanisms of Cantú syndrome-associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel.
Cooper PE, Sala-Rabanal M, Lee SJ, Nichols CG.
J Gen Physiol. 2015 Dec;146(6):527-40. doi: 10.1085/jgp.201511495.
PMID: 26621776
Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway Diseases.
Sala-Rabanal M, Yurtsever Z, Berry KN, Brett TJ.
Mediators Inflamm. 2015;2015:497387. doi: 10.1155/2015/497387. Epub 2015 Nov 3. PMID: 26612971 REVIEW
Role of a Hydrophobic Pocket in Polyamine Interactions with the Polyspecific Organic Cation Transporter OCT3.
Li DC, Nichols CG, Sala-Rabanal M.
J Biol Chem. 2015 Nov 13;290(46):27633-43. doi: 10.1074/jbc.M115.668913. Epub 2015 Sep 24. PMID: 26405039
Secreted CLCA1 modulates TMEM16A to activate Ca(2+)-dependent chloride currents in human cells.
Sala-Rabanal M, Yurtsever Z, Nichols CG, Brett TJ.
Elife. 2015 Mar 17;4:e05875. doi: 10.7554/eLife.05875. PMID: 25781344
Effect of diaminopropionic acid (Dap) on the biophysical properties of a modified synthetic channel-forming peptide.
Bukovnik U, Sala-Rabanal M, Francis S, Frazier SJ, Schultz BD, Nichols CG, Tomich JM.
Mol Pharm. 2013 Oct 7;10(10):3959-66. doi: 10.1021/mp4002377. Epub 2013 Sep 23. PMID: 24010543
Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3.
Sala-Rabanal M, Li DC, Dake GR, Kurata HT, Inyushin M, Skatchkov SN, Nichols CG.
Mol Pharm. 2013 Apr 1;10(4):1450-8. doi: 10.1021/mp400024d. Epub 2013 Mar 19. PMID: 23458604
Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.
Yurtsever Z, Sala-Rabanal M, Randolph DT, Scheaffer SM, Roswit WT, Alevy YG, Patel AC, Heier RF, Romero AG, Nichols CG, Holtzman MJ, Brett TJ.
J Biol Chem. 2012 Dec 7;287(50):42138-49. doi: 10.1074/jbc.M112.410282. Epub 2012 Oct 30. PMID: 23112050
On potential interactions between non-selective cation channel TRPM4 and sulfonylurea receptor SUR1.
Sala-Rabanal M, Wang S, Nichols CG.
J Biol Chem. 2012 Mar 16;287(12):8746-56. doi: 10.1074/jbc.M111.336131. Epub 2012 Jan 30. PMID: 22291026
Bridging the gap between structure and kinetics of human SGLT1.
Sala-Rabanal M, Hirayama BA, Loo DD, Chaptal V, Abramson J, Wright EM.
Am J Physiol Cell Physiol. 2012 May 1;302(9):C1293-305. doi: 10.1152/ajpcell.00397.2011. Epub 2011 Dec 7. PMID: 22159082
Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1.
Peterson LW, Sala-Rabanal M, Krylov IS, Serpi M, Kashemirov BA, McKenna CE.
Mol Pharm. 2010 Dec 6;7(6):2349-61. doi: 10.1021/mp100186b. Epub 2010 Oct 7. PMID: 20929265
Molecular mechanisms of EAST/SeSAME syndrome mutations in Kir4.1 (KCNJ10).
Sala-Rabanal M, Kucheryavykh LY, Skatchkov SN, Eaton MJ, Nichols CG.
J Biol Chem. 2010 Nov 12;285(46):36040-8. doi: 10.1074/jbc.M110.163170. Epub 2010 Aug 31. PMID: 20807765
Molecular biology of K(ATP) channels and implications for health and disease.
Akrouh A, Halcomb SE, Nichols CG, Sala-Rabanal M.
IUBMB Life. 2009 Oct;61(10):971-8. doi: 10.1002/iub.246.
PMID: 19787700 REVIEW
How drugs interact with transporters: SGLT1 as a model.
Loo DD, Hirayama BA, Sala-Rabanal M, Wright EM.
J Membr Biol. 2008 May;223(2):87-106. doi: 10.1007/s00232-008-9116-6. Epub 2008 Jul 1. PMID: 18592293
Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2.
Sala-Rabanal M, Loo DD, Hirayama BA, Wright EM.
Am J Physiol Renal Physiol. 2008 Jun;294(6):F1422-32. doi: 10.1152/ajprenal.00030.2008. Epub 2008 Mar 26. PMID: 18367661
Molecular interactions between dipeptides, drugs and the human intestinal H+ -oligopeptide cotransporter hPEPT1.
Sala-Rabanal M, Loo DD, Hirayama BA, Turk E, Wright EM.
J Physiol. 2006 Jul 1;574(Pt 1):149-66. doi: 10.1113/jphysiol.2006.107904. Epub 2006 Apr 20. PMID: 16627568
Na-dependent D-glucose transport by intestinal brush border membrane vesicles from gilthead sea bream (Sparus aurata).
Sala-Rabanal M, Gallardo MA, Sánchez J, Planas JM.
J Membr Biol. 2004 Sep 15;201(2):85-96. doi: 10.1007/s00232-004-0710-y.
PMID: 15630546