Dr. Zhou’s Publications

  1. Gonzalez-Perez V, Zhou Y, Ciorba Matthew A, Lingle CJ, The LRRC family of BK channel regulatory subunits: potential roles in health and disease, J Physiol. 2022 Jan 10. doi: 10.1113/JP281952.
  2. Zhou, Y., Xia, X.-M., Lingle, C.J. The functionally relevant site for paxilline inhibition of BK channels, Proc Natl Acad Sci U S A. 2019 Dec 26. pii: 201912623. doi: 10.1073/pnas.1912623117;
  3. Lingle CJ, Martinez-Espinosa PL, Yang-Hood A, Boero LE, Payne S, Persic D, V-Ghaffari B, Xiao M, Zhou Y, Xia XM, Pyott SJ, Rutherford MA. LRRC52 regulates BK channel function and localization in mouse cochlear inner hair cells, Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18397-18403. doi: 10.1073/pnas.1907065116;
  4. Zhou, Y., Xia, X.-M., Lingle, C.J. BK channel inhibition by strong extracellular acidification, eLife, 2018 Jul 2;7. pii: e38060. doi: 10.7554/eLife.38060;
  5. Zhou Y, Yang H, Cui J, Lingle CJ, Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel, J Gen Physiol. 2017 Nov 6;149(11):985-1007;
  6. Chen H, Wang L, Wang W, Cheng C, Zhang Y, Zhou Y, Wang C, Miao X, Wang J, Wang C, Li J, Zheng L, Huang K. ELABELA and an ELABELA Fragment Protect against AKI, J Am Soc Nephrol. 2017 Sep;28(9):2694-2707;
  7. Zhou, Y and Lingle, C.J. Engineering differential charge selectivity from a single structural template, Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12610-12612. doi: 10.1073/pnas.1615847113;
  8. Zhou, Y., Xia, X.-M., Lingle, C.J. Cadmium-cysteine coordination in the BK inner pore region and its structural and functional implications, Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5237-42. doi: 10.1073/pnas.1500953112;
  9. Zhou, Y. and Lingle, C.J. Paxilline inhibits BK channels by an almost exclusively closed channel block mechanism, Journal of General Physiology 2014; 144:415-440 ;
  10. Brenker, C., Zhou, Y., Müller, A., Echeverry, FA.,Trotschel, C., Poetsch, A., Xia, XM., Bonigk, W., Lingle, CJ., Kaupp, UB., Strünker, T., The Ca2+-activated K+ current of human sperm is mediated by Slo3, eLife, 2014 Mar 26;3:e01438. doi: 10.7554/eLife.01438.;
  11. Zhou, Y., Zeng, X.-H., and Lingle, C.J. Barium ions selectively activate BK channels via the Ca2+-bowl site. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11413-8;
  12. Yang, C., Zeng, X.-H., Zhou, Y., Xia, X.-M., and Lingle, C.J. LRRC52, a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19419-24;
  13. Zhou, Y., Xia, X.-M., and Lingle, C.J. Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):12161-6;
  14. Zhou, Y., Xia, X.-M., and Lingle, C.J. Inhibition of large-conductance Ca2+-activated K+ channels by nanomolar concentrations of Ag+. Molecular Pharmacology 2010 Nov;78(5):952-60;
  15. Zhou, Y., Tang, Q.-T., Xia, X.-M., and Lingle, C.J. Glycine311, a determinant of paxilline block in BK channels: a novel bend in the BK S6 helix. Journal of General Physiology 2010; 135:481-94;
  16. Zhang, Z., Zhou, Y., Ding, J.-P., Xia, X.-M., and Lingle, C.J. A limited access compartment between the pore domain and cytosolic domain of the BK channel. Journal of Neuroscience 2006; 26:11833-11843.
  17. Zhou, Y., Auerbach A. Gating reaction mechanisms for NMDA receptor channels. Journal of Neuroscience 2005; 25:7914-23
  18. Zhou, Y., Pearson J.E., Auerbach A. Phi-value analysis of a linear, sequential reaction mechanism: theory and application to ion channel gating. Biophys. J. 2005; 89:3680-5;
  19. Shen Y., Zhou Y., Yang XL. Characterization of AMPA receptors on isolated amacrine-like cells in carp retina. Eur. J. Neurosci. 1999; 11:4233-40;