Leung Lab

Daisy W. Leung, Ph.D.

Professor of Medicine
Professor of Pathology & Immunology
Professor of Biochemistry & Molecular Biophysics
Professor of Molecular Microbiology

Department of Internal Medicine
Division of Infectious Diseases
Washington University School of Medicine in St. Louis

B.A. Biology: Amherst College, Amherst, MA
Ph.D. Molecular Biophysics: UT Southwestern, Dallas, TX

Research

The overarching goal of my research program is to define molecular mechanisms at the host-pathogen interface. Within this program, a major focus at present is to define regulatory mechanisms that non-segmented negative-strand RNA viruses (NNSVs), which include human respiratory syncytial virus (RSV) and Ebola virus, use to evade host immunity and hijack the host components to facilitate viral pathogenesis. To achieve this goal, I use a multidisciplinary approach that includes biochemical, structural, biological, and virological methods, to dissect interactions, define structural determinants, and define regulatory mechanisms.