Publications

  1. Crescioli, S., Kaplon, H., Wang, L., Visweswaraiah, J., Kapoor, V., & Reichert, J. M. (2024). Antibodies to watch in 2025. mAbs, 17(1). https://doi.org/10.1080/19420862.2024.2443538
  2. Singh, A. K., L., C.D.; Boas, C.A.W.; Diebolder, P.; Jethva, P.; Rhee, A.; Song, J. H.; Goo, Y. A.; Li, S.; Nickels, M. L.; Liu, Y.; Rogers, B. E.;.; Hallahan, D.E#, Kapoor, V#. Development of [89Zr]Zr-labeled human antibodies using a novel phage-displayed human scFv library. Clin Cancer Res 2024 Jan 26. doi: 10.1158/1078-0432.CCR-23-3647.  #Co-corresponding authors.
  3. Singh AK, Dadey DY, Rau MJ, Fitzpatrick J, Shah HK, Saikia M, Townsend R, Thotala D, Hallahan DE, Kapoor V. Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy. Biomed Pharmacother. 2023 Aug 23;166:115341. doi: 10.1016/j.biopha.2023.115341. Epub ahead of print. PMID: 37625322.
  4. Saikia M, Cheung N, Singh AK, Kapoor V. Role of Midkine in Cancer Drug Resistance: Regulators of Its Expression and Its Molecular Targeting – PubMed (nih.gov) Int J Mol Sci 2023 May 14;24(10):8739. doi: 10.3390/ijms24108739.
  5. Kapoor V, Singh AK, Lewis CD, Deore S, Hallahan DE. Exploiting Radiation Induction of Antigens in Cancer: Targeted Drug Delivery. Int. J. Mol. Sci. 2022, 23(6), 3041.
  6. Campian JL, Ghosh S, Kapoor V, Yan R, Thotala S, Jash A, Hu T, Mahadevan A, Rifai K, Page L, Lee BH, Ferrando-Martinez S, Wolfarth AA, Yang SH, Hallahan D, Chheda MG, Thotala D.Long-Acting Recombinant Human Interleukin-7, NT-I7, Increases Cytotoxic CD8 T Cells and Enhances Survival in Mouse Glioma Models.Clin Cancer Res. 2022 Mar 15;28(6):1229-1239. doi: 10.1158/1078-0432.CCR-21-0947.PMID: 35031547.
  7. Lewis CD, Singh AK, Hsu FF, Thotala D, Hallahan DE, Kapoor V. Targeting a
    Radiosensitizing Antibody-Drug Conjugate to a Radiation-Inducible Antigen.     Clin
    Cancer Res. 2021 Jun 1;27(11):3224-3233. doi: 10.1158/1078-0432.CCR-20-1725.
    PMID: 34074654.
  8. Federico C, Alhallak K, Sun J, Duncan K, Azab F, Sudlow GP, de la Puente P,
    Muz B, Kapoor V, Zhang L, Yuan F, Markovic M, Kotsybar J, Wasden K, Guenthner N,
    Gurley S, King J, Kohnen D, Salama NN, Thotala D, Hallahan DE, Vij R, DiPersio
    JF, Achilefu S, Azab AK. Tumor microenvironment-targeted nanoparticles loaded
    with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma.     Nat
    Commun. 2020 Nov 27;11(1):6037. doi: 10.1038/s41467-020-19932-1. PMID: 33247158;
    PMCID: PMC7699624.
  9. Singh AK, Kapoor V, Thotala D, Hallahan DE. TAF15 contributes to the radiation-inducible stress response in cancer. Oncotarget. 2020 Jul 7;11(27):2647-2659. doi: 10.18632/oncotarget.27663. PMID: 32676166; PMCID: PMC7343639.
  10. Kapoor V, Collins A, Griffith K, Ghosh S, Wong N, Wang X, Challen GA, Krambs J, Link D, Hallahan DE, Thotala D. Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow. Oncotarget. 2020 May 12;11(19):1681-1690. doi: 10.18632/oncotarget.27564. PMID: 32477458; PMCID: PMC7233802.
  11. Kapoor V, Singh AK, Rogers BE, Thotala D, Hallahan DE. PEGylated peptide to TIP1 is a novel targeting agent that binds specifically to various cancers in vivo. J Control Release. 2019 Mar 28;298:194-201. doi: 10.1016/j.jconrel.2019.02.008. Epub 2019 Feb 11. PMID: 30763622; PMCID: PMC6557269.
  12. Dadey DYA, Kapoor V, Khudanyan A, Thotala D, Hallahan DE. PERK Regulates Glioblastoma Sensitivity to ER Stress Although Promoting Radiation Resistance. Mol Cancer Res. 2018 Oct;16(10):1447-1453. doi: 10.1158/1541-7786.MCR-18-0224. Epub 2018 Jul 10. PMID: 29991528.
  13. Riehl TE, Alvarado D, Ee X, Zuckerman A, Foster L, Kapoor V, Thotala D, Ciorba MA, Stenson WF. Lactobacillus rhamnosus GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells. Gut. 2019 Jun;68(6):1003-1013. doi: 10.1136/gutjnl-2018-316226. Epub 2018 Jun 22. PMID: 29934438; PMCID: PMC7202371.
  14. Puente P, Fettig N, Luderer MJ, Jin A, Shah S, Muz B, Kapoor V, Goddu SM, Salama NN, Tsien C, Thotala D, Shoghi K, Rogers B, Azab AK. Injectable Hydrogels for Localized Chemotherapy and Radiotherapy in Brain Tumors. J Pharm Sci. 2018 Mar;107(3):922-933. doi: 10.1016/j.xphs.2017.10.042. Epub 2017 Nov 21. PMID: 29162424; PMCID: PMC6093750.
  15. Dadey DYA, Kapoor V, Hoye K, Khudanyan A, Collins A, Thotala D, Hallahan DE. Antibody Targeting GRP78 Enhances the Efficacy of Radiation Therapy in Human Glioblastoma and Non-Small Cell Lung Cancer Cell Lines and Tumor Models. Clin Cancer Res. 2017 May 15;23(10):2556-2564. doi: 10.1158/1078-0432.CCR-16-1935. Epub 2016 Nov 4. PMID: 27815359.
  16. Kapoor V, Dadey DY, Nguyen K, Wildman SA, Hoye K, Khudanyan A, Bandara N, Rogers BE, Thotala D, Hallahan DE. Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers. J Nucl Med. 2016 Dec;57(12):1991-1997. doi: 10.2967/jnumed.115.165118. Epub 2016 Jul 21. PMID: 27445290; PMCID: PMC5126697.
  17. Yan H, Kapoor V, Nguyen K, Akers WJ, Li H, Scott J, Laforest R, Rogers B, Thotala D, Hallahan D. Anti-tax interacting protein-1 (TIP-1) monoclonal antibody targets human cancers. Oncotarget. 2016 Jul 12;7(28):43352-43362. doi: 10.18632/oncotarget.9713. PMID: 27270318; PMCID: PMC5190028.
  18. Luderer MJ, Muz B, de la Puente P, Chavalmane S, Kapoor V, Marcelo R, Biswas P, Thotala D, Rogers B, Azab AK. A Hypoxia-Targeted Boron Neutron Capture Therapy Agent for the Treatment of Glioma. Pharm Res. 2016 Oct;33(10):2530-9. doi: 10.1007/s11095-016-1977-2. Epub 2016 Jul 11. PMID: 27401411; PMCID: PMC5007153.
  19. Dadey DY, Kapoor V, Khudanyan A, Urano F, Kim AH, Thotala D, Hallahan DE. The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma. Oncotarget. 2016 Jan 12;7(2):2080-92. doi: 10.18632/oncotarget.6712. PMID: 26716508; PMCID: PMC4811517.
  20. Kapoor V, Aggarwal S, Das SN. 6-Gingerol Mediates its Anti Tumor Activities in Human Oral and Cervical Cancer Cell Lines through Apoptosis and Cell Cycle Arrest. Phytother Res. 2016 Apr;30(4):588-95. doi: 10.1002/ptr.5561. Epub 2016 Jan 7. PMID: 26749462.
  21. Kapoor V, Khudanyan A, de la Puente P, Campian J, Hallahan DE, Azab AK, Thotala D. Stem Cell Transfusion Restores Immune Function in Radiation-Induced Lymphopenic C57BL/6 Mice. Cancer Res. 2015 Sep 1;75(17):3442-5. doi: 10.1158/0008-5472.CAN-15-1412. Epub 2015 Jun 30. PMID: 26130648.
  22. Kumar S, Jitendra K, Singh K, Kapoor V, Sinha M, Xess I, Das SN, Sharma S, Singh TP, Dey S. Biological Properties and Characterization of ASL50 Protein from Aged Allium sativum Bulbs. Appl Biochem Biotechnol. 2015 Aug;176(7):1914-27. doi: 10.1007/s12010-015-1687-y. Epub 2015 Jun 5. PMID: 26043852.
  23. Kumar S, Kapoor V, Gill K, Singh K, Xess I, Das SN, Dey S. Antifungal and antiproliferative protein from Cicer arietinum: a bioactive compound against emerging pathogens. Biomed Res Int. 2014;2014:387203. doi: 10.1155/2014/387203. Epub 2014 May 14. PMID: 24963482; PMCID: PMC4053179.
  24. Gill K, Singh AK, Kapoor V, Nigam L, Kumar R, Holla P, Das SN, Yadav S, Subbarao N, Mohanti BK, Dey S. Development of peptide inhibitor as a therapeutic agent against head and neck squamous cell carcinoma (HNSCC) targeting p38alpha MAP kinase. Biochim Biophys Acta. 2013 Mar;1830(3):2763-9. doi: 10.1016/j.bbagen.2012.12.001. PMID: 23238519.
  25. Garg R, Kapoor V, Mittal M, Singh MK, Shukla NK, Das SN. Abnormal expression of PI3K isoforms in patients with tobacco-related oral squamous cell carcinoma. Clin Chim Acta. 2013 Feb 1;416:100-6. doi: 10.1016/j.cca.2012.11.027. Epub 2012 Dec 7. PMID: 23228846.
  26. Karimi MY, Kapoor V, Sharma SC, Das SN. Genetic polymorphisms in FAS (CD95) and FAS ligand (CD178) promoters and risk of tobacco-related oral carcinoma: gene-gene interactions in high-risk Indians. Cancer Invest. 2013 Jan;31(1):1-6. doi: 10.3109/07357907.2012.743555. Epub 2012 Nov 15. PMID: 23153021.
  27. Kapoor V, Paliwal D, Baskar Singh S, Mohanti BK, Das SN. Deregulation of Beclin 1 in patients with tobacco-related oral squamous cell carcinoma. Biochem Biophys Res Commun. 2012 Jun 15;422(4):764-9. doi: 10.1016/j.bbrc.2012.05.079. Epub 2012 May 22. PMID: 22627130.
  28. Singh AK, Singh R, Naz F, Chauhan SS, Dinda A, Shukla AA, Gill K, Kapoor V, Dey S. Structure based design and synthesis of peptide inhibitor of human LOX-12: in vitro and in vivo analysis of a novel therapeutic agent for breast cancer. PLoS One. 2012;7(2):e32521. doi: 10.1371/journal.pone.0032521. Epub 2012 Feb 23. PMID: 22384268; PMCID: PMC3285689.
  29. Kapoor V, Zaharieva MM, Das SN, Berger MR. Erufosine simultaneously induces apoptosis and autophagy by modulating the Akt-mTOR signaling pathway in oral squamous cell carcinoma. Cancer Lett. 2012 Jun 1;319(1):39-48. doi: 10.1016/j.canlet.2011.12.032. Epub 2011 Dec 24. PMID: 22202640.
  30. Mittal M, Kapoor V, Mohanti BK, Das SN. Functional variants of COX-2 and risk of tobacco-related oral squamous cell carcinoma in high-risk Asian Indians. Oral Oncol. 2010 Aug;46(8):622-6. doi: 10.1016/j.oraloncology.2010.06.002. PMID: 20620096.
  31. Kapoor V, Singh AK, Dey S, Sharma SC, Das SN. Circulating cycloxygenase-2 in patients with tobacco-related intraoral squamous cell carcinoma and evaluation of its peptide inhibitors as potential antitumor agent. J Cancer Res Clin Oncol. 2010 Dec;136(12):1795-804. doi: 10.1007/s00432-010-0837-4. Epub 2010 Mar 6. PMID: 20213098.