Our research interests in inter-organ communication extend to multiple diseases, including COVID-19 and Alzheimer’s disease, as well as muscle regeneration and aging

Education

UT Southwestern Medical Center (Postdoc)

Eric Olson lab

Research Projects

Brain-muscle communication in infectious disease

Brain-muscle communication in chronic disease

Brain-muscle communication in aging

Exercise as a treatment for Alzheimer’s disease

Systemic muscle injury and repair

Epidermis-muscle stem cell communication in regeneration

Genetic models of cerebral palsy

Genetic models of rare genetic diseases

Featured Publications
Infection and chronic disease activate a systemic brain-muscle signaling axis

S Yang*, M Tian*, Y Dai, R Wang, S Yamada, S Feng, Y Wang, D Chhangani, T Ou, W Li, X Guo, J McAdow, DE Rincon-Limas, X Yin, W Tai, G Cheng, AN Johnson, Sci Immunol 2024 July

The brain-muscle signaling axis in the media
Spatiotemporal expression of regulatory kinases directs the transition from mitosis to cellular morphogenesis in Drosophila

S Yang, J McAdow, Y Du, J Trigg, PH Taghert, AN Johnson, Nat Comms 2022 Feb

A pathogenic mechanism associated with myopathies and structural birth defects involves TPM2-directed myogenesis

J McAdow, S Yang, T Ou, G Huang, MB Dobbs, CA Gurnett, MJ Greenberg, AN Johnson JCI Insights 2022 May

FGF signaling directs myotube guidance by regulating Rac activity

S Yang, A Weske, Y Du, JM Valera, KL Jones, AN Johnson Development 2020 Feb

Link to complete bibliography