Kelsey Tinkum

Program Years: 2009-2010

Mentors:  

Primary: Helen Piwnica

Graduate Thesis Title: Characterization of Fasting-Induced p21 Expression and Protection of Intestinal Stem Cells

Publications: 

Tinkum, K. L., Marpegan, L., White, L. S., Sun, J., Herzog, E. D., Piwnica-Worms, D., & Piwnica-Worms, H. (2011). Bioluminescence imaging captures the expression and dynamics of endogenous p21 promoter activity in living mice and intact cells. Molecular and cellular biology, 31(18), 3759-3772.

Tinkum, K. L., White, L. S., Marpegan, L., Herzog, E., Piwnica-Worms, D., & Piwnica-Worms, H. (2013). Forkhead box O1 (FOXO1) protein, but not p53, contributes to robust induction of p21 expression in fasted mice. Journal of Biological Chemistry, 288(39), 27999-28008.

Wang, Y. V., Leblanc, M., Fox, N., Mao, J. H., Tinkum, K. L., Krummel, K., … & Kaushansky, K. (2011). Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes & development, 25(13), 1426-1438.