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Nearly all organisms have a biological clock that keeps daily time. Biological clocks that drive near 24-hour rhythms in behavior and physiology have been found in a wide variety of organisms and cell types. The Herzog Lab studies the molecules, cells and circuits underlying these circadian rhythms in mammals using techniques that include planar electrode arrays, real-time cellular imaging and genetic manipulations (i.e. mutants, knockouts, transgenics, optogenetics, etc.). This approach is producing insight into the roles of specific neuropeptides and cell types in the rich repertoire of daily behaviors. We currently focus on circadian regulation in and by the suprachiasmatic nucleus (SCN) of the hypothalamus, the olfactory bulb (OB), and astroglial cells of the neocortex. We ask questions like: Which cells generate these rhythms? How do they synchronize to one another? What are the consequences when their rhythms are disrupted?

St. Louis Neuroscience Outreach  |  WUSTL Biology  |  Brain Bee  |  Undergraduate Neurotrack  |  Graduate Neuroscience  |  ENDURE  |  COBRAS  

Contact us

Erik Herzog, PhD.

Washington University in St. Louis
Campus Box: 1137
One Brookings Drive
St. Louis, MO 63130-4899

Office: Bayer 205
Phone: (314) 935-8635
Email: herzog@wustl.edu
Twitter: @ErikHerzog

Lab: Bayer 204
Lab Phone: (314) 935-3330