Pre-prints
We are committed to accessible science and understand the value of pre-prints. The following are a selection of our current manuscripts under review.
Systematic characterization of brain cellular crosstalk signaling networks in Alzheimer’s disease reveals a novel role for SEMA6D in TREM2-dependent microglial activation
Ricardo D’Oliveira Albanus, Gina M. Finan, Logan Brase, Shuo Chen, Qi Guo, Abhirami Kannan, Mariana Acquarone, Shih-Feng You, Brenna C Novotny, Patricia M Ribeiro Pereira, John C Morris, Randall J Bateman, Eric McDade, Carlos Cruchaga, Jasmeer P Chhatwal, Dominantly Inherited Alzheimer Network (DIAN), Emily E Mace, Bruno A Benitez, Laura Piccio, Greg T Sutherland, Qin Ma, Hongjun Fu, Celeste M Karch, Oscar Harari, Tae-Wan Kim
bioRxiv 2022.11.11.516215; doi: https://doi.org/10.1101/2022.11.11.516215
Phospholipase D3 contributes to Alzheimer’s disease risk via disruption of Aβ clearance and microglia response to amyloid plaques
Matthew J. Rosene, Simon Hsu, Shih Feng You, Logan Brase, Anthony Verbeck, Rita Martinez, Clare E. Wallace, Zeran Li, Ping Yan, Nina M. Dräger, Sydney M. Sattler, Abhirami K Iyer, Shannon L Macauley, David M. Holtzman, Bruno A. Benitez, Martin Kampmann, Carlos Cruchaga, Oscar Harari, John R. Cirrito, Jin-Moo Lee, Alison M. Goate, Celeste M. Karch
medRxiv 2022.01.31.22270175; doi: https://doi.org/10.1101/2022.01.31.22270175
Cross-omics integration shows cortex-wide synaptic dysfunction at later stages of Alzheimer disease
Abdallah M. Eteleeb, Brenna C. Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A. Davis, John C. Morris, Celeste M. Karch, Richard J. Perrin, Bruno A. Benitez, Oscar Harari
https://www.medrxiv.org/content/10.1101/2022.12.10.22283295v1.full-text