Oscar Harari, PhD

I have the privilege of leading a multicultural and diverse multidisciplinary research group that brings together computational biologists, systems biologists, and bioinformaticians to study Alzheimer disease, related dementias and neurodegeneration. We use traditional statistical and advanced machine learning and data science approaches to analyze molecular data and provide novel insights on neurodegeneration.

Our work aims to discern how genetic factor and genes contribute to the biological processes that affect disease using multi-omic integrative approaches with particular emphases in single-cell molecular data and spatially resolved transcriptomics. We develop and use innovative analytical workflows to study the genetic, transcriptomic, proteomic, metabolomic, and epigenetic data from tissue homogenates and single-cell brain tissue.