Stem Cells and Regeneration
Luis F. Z. Batista, PhD
Understanding the role of telomerase and other ribonucleoproteins during tissue homeostasis, regeneration, aging, and cancer
Grant Challen, PhD
Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells.
Milan Chheda, MD
Identifying and characterizing the genetic and epigenetic events that induce cancer and maintain tumors.
Kyunghee Choi, PhD
We study molecular mechanisms that regulate hematopoietic and vascular development and regeneration.
Brian Clark, PhD
Analysis of the temporally regulated program of retinal cell type specification.
David Curiel, MD, PhD
To address the central mandate of gene therapy we engineer adenovirus tropism to allow the achievement of effective gene delivery.
Matthew Goldsmith, MD
My lab is interested in skeletal biology and growth control, including growth during normal ontogeny and during the regeneration of tissues/organs.
Michael Greenberg, PhD
The Greenberg lab seeks to understand the molecular and cellular biophysics of heart disease, with the goal of engineering disease models and precision therapeutics.
Farshid Guilak, PhD
We focus on the role of biomechanical factors in the onset, progression, and treatment of osteoarthritis and other joint diseases.
David Gutmann, MD, PhD
Leveraging neurogenetic disorders to study normal brain development, cancer, and behavior.
Benjamin Humphreys, MD, PhD
Define cell hierarchies in kidney injury and repair and thereby identify the critical cell types in kidney repair and fibrosis.
Sanjay Jain, MD, PhD
The Jain lab studies interactions between the nervous and genitourinary systems during development, molecular basis for heterogeneity in progenitors and their lineage commitments in the GU tract, injury and regeneration using animal models, mechanisms of malformations using organoids from iPSCs.
Celeste Karch, PhD
The goal of my research is to understand the molecular and cellular mechanisms underlying tauopathies.
Kristen Kroll, PhD
Transcriptional and epigenetic regulation of neural development and its dysregulation in neurodevelopmental disorders.
Kory Lavine, MD, PhD
Identify signaling pathways that mediate cardiac tissue repair/regeneration and heart failure pathogenesis.
Susan Mackinnon, MD
The overall focus of the Mackinnon Laboratory is to investigate the pathology, mechanisms, and current/prospective clinical treatments of peripheral nerve injury.
Jeffrey Magee, MD, PhD
Developmental context and genetic variation as underlying mechanisms of childhood cancer.
Helen McNeill, PhD
DRSCB Program Co-Director
The overall goal of research in the McNeill lab is to understand at a cellular level how tissue growth and tissue organization are regulated during normal development, and how loss of this control leads to human disease.
Gretchen Meyer, PhD
Understanding how changes at the molecular and cellular level in skeletal muscle affect muscle structure and function
Craig Micchelli, PhD
Our laboratory investigates the basis of stem cell behavior in their native tissue microenvironments.
Jeffrey Millman, PhD
The Millman laboratory is focused on the use of stem cells for the study and treatment of diabetes.
Samantha Morris, PhD
Developing new single-cell technologies to create high-resolution maps of lineage and identity; Manipulating gene regulatory networks, via direct lineage reprogramming, to generate clinically valuable cell types.
David Ornitz, MD, PhD
Regulation of lung, skeletal, and cardiovascular development, injury response, and regeneration by Fibroblast Growth Factors.
Deborah Rubin, MD, PhD
Intestinal stem cells and the stem cell niche in intestinal injury/short bowel syndrome and colitis associated colon cancer.
Erica Scheller, DDS, PhD
Impact of neuroendocrine signals on bone loss and marrow adiposity in diseases including periodontitis, arthritis, and diabetes.
Laura Schuettpelz, MD, PhD
The Schuettpelz Lab is interested in understanding how inflammatory signals regulate hematopoietic stem cells (HSCs).
Lori Setton, PhD
Understanding the mechanisms for degeneration and regeneration of soft tissues of the musculoskeletal system, including the intervertebral disc, articular cartilage, and meniscus.
Lavinia Sheets, PhD
Defining pathological changes in noise-exposed sensory hair cells and identifying pathways that promote repair.
Lilianna Solnica-Krezel, PhD
Inductive and morphogenetic processes that establish and shape germ layers during vertebrate embryogenesis, using zebrafish and embryonic stem cell models.
Amber Stratman, PhD
Understanding the normal developmental processes regulating mural cell stabilization of the vasculature as a platform to assess alterations in signaling pathways during disease.
Thorold Theunissen, PhD
Exploring the molecular regulation and applications of pluripotent stem cells.
Mark Warchol, PhD
Mechanisms of development, injury and repair in the vertebrate auditory system.
Philip Williams, PhD
Strategies to improve outcomes of nervous system injury and disease, regeneration and preservation.
Lab website
Andrew Yoo, PhD
The general goal of our research is to understand genetic mechanisms underlying neurogenesis and develop cellular reprogramming approaches to generate human neurons by directly converting dermal fibroblasts.