Publication Announcement

Examining the Role of SARM1 in a Mouse Model of Glaucoma

A recent JCB paper from postdoc Kwang Woo Ko looks at Sarm1’s role in glaucoma.  He shows that knocking out Sarm1 protects retinal ganglion cells and axons in a mouse model of glaucoma. His experiments demonstrate that neuroinflammatory and necroptotic signaling work through SARM1 to drive axon loss.