Another passion is generating real world data to guide clinical care. I co-founded a consortium of 11 IBD centers that have agreed to participate in the expanded REBOOT consortium that has grown from the TROPIC consortium studies of TOFA and ustekinumab. The group has received funding from BMS to study ozanimod in UC and from AbbVie to study upadacitinib in UC.
Sites
- Division of Gastroenterology, Washington University in Saint Louis School of Medicine, St. Louis, MO, USA. Site PI – Parakkal Deepak, MBBS, MS
- Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mt. Sinai, New York, New York, USA. Site PI – Ryan C. Ungaro, MD, MS
- Division of Gastroenterology, Cedars Sinai, LA, CA. Site PIs – Andres Yarur, MD
- Section of Gastroenterology, Hepatology and Nutrition, University of Chicago Department of Medicine, Chicago, Illinois, USA. Site PI – Joel Pekow, MD
- Division of gastroenterology, Brooke Army Medical Center, Fort Sam Houston, Texas, USA. Site PI – Anish Patel, MD
- Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Site PI – Amanda Johnson, MD
- Division of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio – Site PI – Benjamin Cohen, MD
- Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI – Site PI – Shrinivas Bishu, MD
- Division of Gastroenterology and Hepatology, Baylor college of Medicine, Houston, Tx – Site PI – Richa Shukla, MD
- Division of Gastroenterology and Hepatology, Albert Einstein School of Medicine, Bronx, NYC – Site PI – Tom Ullman, MD
- Division of gastroenterology, Thomas Jefferson University, Philadelphia, Pennsylvania – Site PI – Raina Shivashankar, MD
- Yarur AJ, Ungaro R, Huang K, Wang W, Sasankan P, Zulqarnain M, Johnson AM, Bader G, Kay C, Costable N, Dulaney D, Fenster M, Beniwal-Patel P, Syal G, Patel A, Loftus E Jr, Pekow J, Cohen B, Deepak P. Real-World Effectiveness of Ustekinumab in Ulcerative Colitis in a United States Multicenter Cohort Consortium. Inflamm Bowel Dis. 2025 Jan 6;31(1):131-139. PMID: 38531068
- Fenster M, Alayo QA, Khatiwada A, Wang W, Dimopoulos C, Gutierrez A, Ciorba MA, Christophi GP, Hirten RP, Ha C, Beniwal-Patel P, Cohen BL, Syal G, Yarur A, Patel A, Colombel JF, Pekow J, Ungaro RC, Rubin DT, Deepak P. Real-World Effectiveness and Safety of Tofacitinib in Crohn’s Disease and IBD-U: A Multicenter Study From the TROPIC Consortium. Clin Gastroenterol Hepatol. 2021 Oct;19(10):2207-2209.e3. PMID: 33068786
- Deepak P, Alayo QA, Khatiwada A, Lin B, Fenster M, Dimopoulos C, Bader G, Weisshof R, Jacobs M, Gutierrez A, Ciorba MA, Christophi GP, Patel A, Hirten RP, Colombel JF, Rubin DT, Ha C, Beniwal-Patel P, Ungaro RC, Syal G, Pekow J, Cohen BL, Yarur A. Safety of Tofacitinib in a Real-World Cohort of Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 2021 Aug;19(8):1592-1601.e3. PMID: 32629130