Welcome to the Colonna Lab
![](https://sites.wustl.edu/colonnalab/files/2018/03/CS1-002-1s4fzvl.jpg)
Microfold cells in the follicle-associated epithelium overlying a Peyer’s patch
The laboratory is broadly interested in innate immunity, focused on three main areas:
1) Innate lymphoid cells (ILCs) in mucosal immunity
2) Innate immune mechanisms in Alzheimer`s disease and neurodegeneration
3) Plasmacytoid dendritic cells and IFNα/β in host defense and autoimmunity
![](https://sites.wustl.edu/colonnalab/files/2018/03/DSC_8673-1o1031t-1024x684.jpg)
We are located in the BJC Institute of Health building at Washington University in St. Louis on the School of Medicine campus in the Central West End.
Current lab members
![](https://sites.wustl.edu/colonnalab/files/2019/06/Image-1024x1024.jpg)
Plaque-associated microglia in the 5xFAD mouse model. Stainings: Iba1 (microglia, green), Abeta1-42 (Abeta plaques, white), DAPI (nuclei, blue).