| June, 1988 | CLEK Study concept initiated at the first Clinical Trials Workshop, sponsored by the AOA Council on Research and the American Academy of Optometry Research Committee. |
| Sept. 1, 1989 | National Eye Institute (NEI) funding received for pilot study:
Contact Lens Evaluation in Keratoconus Screening Grant – R21 EY08650
(The Ohio State University, PI: Joe Barr, OD, MS) |
| March, 1990 | NEI Planning grant funded (R21 EY08652-01). Weekly conference calls initiated between Drs. Barr, Edrington, Gordon and Zadnik. |
| Sept. 30, 1994 – Sept. 29, 1999 | NEI Funding received for Collaborative Longitudinal Evaluation in Keratoconus Study (CLEK):- Chairman’s Office – U10 EY10419 (University of California @ Berkeley, PI: Karla Zadnik, OD)
- Cornea Photography Reading Center – U10 EY10069 (The Ohio State University, PI: Joe Barr, OD, MS)
- Coordinating Center – U10 EY10077 (Washington University School of Medicine, PI: Mae Gordon, PhD)
|
| Dec. 13, 1994 | First Executive Committee Meeting, Orlando, FL |
| Dec. 14, 1994 | First Full Investigative Group Meeting (FIG), Orlando, FL |
| Feb. 15, 1995 | First Data Monitoring & Oversight Committee Meeting, Berkeley, CA |
| Apr. 8 & 9, 1995 | Training Meeting in Columbus, OH |
| May 31, 1995 | First Patient Enrolled |
| Nov. 2 & 3, 1995 | First Site Visit, Birmingham, AL |
| May 23, 1996 | CLEK Photography Reading Center (CPRC) Site Visit, Columbus, OH by Larry Hubbard, MAT (Associate Director of Fundus Photograph Reading Center, University of Wisconsin @ Madison) |
| Jun. 29, 1996 | Last Patient Enrolled |
| Jun. 19, 1997 | Coordinating Center Site Visit, St. Louis, MO by Maureen Maguire, PhD (Associate Professor, University of Pennsylvania, Scheie Eye Institute) |
| Dec., 1998 | Publication of Baseline Paper in Investigative Ophthalmology & Visual Science |
| Sept. 30, 1999 – Sept. 29, 2004 | NEI Funding received for Collaborative Longitudinal Evaluation in Keratoconus Study (CLEK): - Chairman’s Office – U10 EY10419 (The Ohio State University, PI: Karla Zadnik, OD, PhD)
- Cornea Photography Reading Center – U10 EY10069 (The Ohio State University, PI: Joe Barr, OD, MS)
- Coordinating Center – U10 EY10077 (Washington University School of Medicine, PI: Mae Gordon, PhD)
|
| Sept. 1, 1999 – Aug. 31, 2004 | NEI Funding received for Collaborative Longitudinal Evaluation in Keratoconus Study (CLEK): - Cornea Topography Reading Center – U10 EY12656 (University of Illinois @ Chicago, PI: Tim McMahon, OD)
|
| Jun. 7, 2000 | Coordinating Center Site Visit, St. Louis, MO by Fran LoPresti (Manager, EDI, Magellan Behavioral Health) |
| Feb. 2, 2001 | CLEK Topography Reading Center (CTRC) Monitoring Visit by Larry Hubbard, MAT (Associate Director of Fundus Photograph Reading Center, University of Wisconsin @ Madison) |
| Apr. 9, 2003 | First Year 8 Close-out Visit |
| Aug. 5, 2004 | Last Year 8 Close-out Visit |
| Sept. 30, 2004 – Sept. 29, 2005 | NEI funding received: - Chairman’s Office – U10 EY10419 (The Ohio State University, PI: Karla Zadnik, OD, PhD)
- Cornea Photography Reading Center – U10 EY10069 (The Ohio State University, PI: Joe Barr, OD, MS)
- Coordinating Center – U10 EY10077 (Washington University School of Medicine, PI: Mae Gordon, PhD)
|
| Sept. 1, 2004 – Aug. 31, 2005 | NEI Funding received for Collaborative Longitudinal Evaluation in Keratoconus Study (CLEK): |