Selected Publication

2022

  1. Feng R, Cavalli V. (2022) Self Renewing Macrophages in Dorsal Root Ganglia Contribute to Promote Nerve Regeneration. Sneak Peak under review at Cell Reports May 13, 2022, >Full Article
  2. Avraham O,  Chamessian A, Feng R, Yang L, Halevi A, Moore A, Gereau R, Cavalli V. (2022) Profiling the Molecular Signature of Satellite Glial Cells at the single cell level Reveals High Similarities Between Rodents and Humans. Pain March 31, 2022, >Full Article >Press Release
  3. Deng P-Y, Kumar A, Cavalli V, Klyachko VA (2022) FMRP regulates GABAa receptor channel activity to control signal integration in hippocampal granule cells. Cell Reports. 39(7):110820. doi: https://doi.org/10.1016/j.celrep.2022.110820.>Full Article
  4. Avraham O, Deng P, Maschi D, Klyachko V, Cavalli V. (2022) Disrupted Association of Sensory Neurons With Enveloping Satellite Glial Cells in Fragile X Mouse Model. Frontiers in Molecular Neuroscience January 2022 (14) Article number 796070 >Full Article Resources Available
2021
  1. Deng P, Avraham O, Cavalli V, Klyachko V. (2021) Hyperexcitability of Sensory Neurons in Fragile X Mouse Model. Frontiers in Molecular Neuroscience December 2021 (14) Article number 796053 >Full Article
  2. Avraham O, Feng R, Ewan EE, Zhao G, Cavalli V. (2021)  Profiling sensory neuron microenvironment after peripheral and central axon injury reveals key pathways for axon regeneration. Elife 10:e68457 >Full article >Press Release Resources Available
  3. Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo cJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic  A, Joshita  S,  Kubo M , Gereau 4th  RW, Alexander-Brett  J, Cavalli  V,  Davidson  S, Hu  H , Liu  Q , Kim  BS. (2021) 12IL-33 Signaling in Sensory Neurons Promotes Dry Skin Itch J Allergy Clin Immunol S0091-6749(21)01405-6. >Full article
  4. Spears LD, Adak S, Dong G, Wei X, Spyropoulos G, Zhang Q, Yin L, Feng C, Hu D, Lodhi IJ, Hsu F-, Rajagopal R, Noguchi KK, Halabi CM, Brier L, Bice AR, Lananna BV, Musiek ES, Avraham O, Cavalli V, Holth JK, Holtzman DM, Wozniak DF, Culver JP, Semenkovich CF. (2021) Endothelial ether lipids link the vasculature to blood pressure, behavior, and neurodegeneration. J. Lipid Res. 2021 Apr 21;62:100079. doi: 10.1016/j.jlr.2021.100079. >Full article. PMID: 3389421.
  5. Avraham O, Charmessian A, Feng R, Halevi AE, Moore AM, Gereau RW and Cavalli V. (2021) Profiling the molecular signature of Satellite Glial Cells at the single cell level reveals high similarities between rodent and human. >Pre-print
  6. Pita-Thomas W, Mangetti Concalves T, Zhao G and Cavalli V (2021) Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration. Scientific Reports (11), Article number: 14924   >Full Article
2020
  1. Ewan, E.E., Avraham O, Carlin, D., Goncalves, T.M., Zhao, G. and Cavalli V. (2020) Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism. Scientific Reports 2021; 11: 374.>Full article
  2. Avraham O, Deng P-Y, Jones S, Kuruvilla R, Semenkovich CF, Klyachko VA, Cavalli V (2020). Satellite glial cells promote regenerative growth in sensory neurons. Nature Communications 11, 4891 >Full article Resources Available
2019
  1. Carlin D, Halevi A, Ewan EE, Moore A, and Cavalli V. (2019). Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia.  eNeuro, Jun 25;6(3). pii ENEURO.0168-19. 2019  >>Full article
  2. Pita-Thomas W, Mahar M, Joshi A, Gan D, Cavalli V. (2019). HDAC5 promotes Optic Nerve Regeneration in Retinal Ganglion cells. Exp. Neurology, 317:217-283.>Full article.
  3. Balkunde R, Foroughi L, Ewan E, Emenecker R, Cavalli V and Dixit R. (2019). Mechanism of microtubule plus-end tracking by the plant-specific SPR1 protein and its development as a versatile plus-end marker. J Biol Chem. 2019 Sep 16. . >Full article.
2018
  1. Oh YM, and Mahar M, Ewan E, Leahy K, Zhao G, and Cavalli V (2018). The epigenetic regulator UHRF1 inactivates REST and growth suppressor gene expression via DNA methylation to promote axon regeneration. Proceedings of the National Academy of Sciences Dec 2018, 115(52) E12417-E12426> Full article 
  2. Carlin D, Golden JP, Mogha A, Samineni VK, Monk KR, Gereau RW 4th, Cavalli V. (2018). Deletion of Tsc2 in Nociceptors Reduces Target Innervation, Ion Channel Expression, and Sensitivity to Heat. eNeuro. 2018 May 3;5(2). >Full article
  3. Mahar M, Cavalli V. (2018). Intrinsic mechanisms of neuronal axon regeneration.  Nature Reviews Neuroscience 2018 Apr 17. Review.> Full article 
  4. Pita Thomas W, Barroso-Garcia G, Moral V, Hackett A, Cavalli V, Nieto-Diaz, M. (2017). Identification of axon growth promoters in the secretome of the deer antler velvet. Neuroscience, 340:333-344. > Full article
2017
  1. Ban N, Siegfried CJ, Lin JB, Shui YB, Sein J, Pita-Thomas W, Sene A, Santeford A, Gordon M, Lamb R, Dong Z, Kelly SC, Cavalli V, Yoshino J, Apte RS. (2017). GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients. JCI Insight. 2017 May 4;2(9). > Full article 
2016
  1. Mogha A, Harty BL, Carlin D, Joseph H, Sanchez NE, Suter U, Piao X, Cavalli V, Monk KR. (2016). Gpr126/Adgrg6 has Schwann cell autonomous and non-autonomous functions in peripheral nerve injury and repair. J Neuroscience, 36(49):12351-12367. > Full article
  2. Saito A and Cavalli V. (2016). Signaling over Distances. Mol Cell Proteomics. 15:382-93. > Full article 
2015
  1. Cho Y, Shin JE, Ewan EE, Oh YM, Pita-Thomas W and Cavalli V (2015) Activating injury-responsive genes with hypoxia enhances axon regeneration through neuronal HIF-1α. Neuron, 18:720-34 > Full article
  2. Cho Y, Park D and Cavalli V. (2015). Filamin A is required in injured axons for HDAC5 activity and axon regeneration. J Biol Chem, 290(37):22759-70. > Full article 
  3. Watt D, Dixit R and Cavalli V. (2015). JIP3 activates kinesin-1 motilty to promote axon elongation. J Biol Chem, 290(25):15512-25 . > Full article
  4. Song W*, Cho Y*, Watt, D Cavalli, V. (2015). Tubulin-tyrosine ligase (TTL)-mediated increased in tyrosinated α-tubulin in injured axons is required for retrograde injury signaling and axon regeneration. J Biol Chem, 290(23):14765-75. > Full article
2014
  1. Cho Y*, DiLiberto V*, Carlin D, Li KH, Guan S, Michaelevski I, Abe N, Burlingame A, Cavalli V. (2014). Syntaxin13 expression is regulated by mammalian target of rapamycin (mTOR) in injured neurons to promote axon regeneration. J. Biol. Chem. 289 (22);15820-15832. > Full article 
  2. Cho Y and Cavalli V. (2014) .HDAC signaling in neuronal development and axon regeneration. Curr Opin Neurobiol. 27: 188-126. > Full article 
2013
  1. Cho Y, Sloutsky R, Naegle KM and Cavalli V. (2013). Injury-induced HDAC5 nuclear export is essential for axon regeneration. Cell, 155, 894-908. > Full article
2012
  1. Shin JE, Miller BR, Babetto E, Cho Y, Sasaki Y, Qayuma S, Russlera EV, Cavalli V, Milbrandt J, DiAntonio A. (2012). SCG10 is a JNK target in the axonal degeneration pathway. PNAS, 109(52):E3696-705. > Full article 
  2. Cho Y and Cavalli V. (2012). HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration. EMBO Journal, Jun 12. > Full article 
  3. Shin JE, Cho Y, Beirowski B, Milbrandt J, Cavalli V and DiAntonio A. (2012). Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. Neuron, 74(6) 1015-1022. > Full article
  4. Di Liberto V and Cavalli V. (2012). Ready, STAT, go: transcription factors on the move. EMBO Journal, 31(6):1331-3. PMC3321183 > Full article
2011
  1. Sun F, Zhu Z, Dixit R and Cavalli V. (2011). Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility. EMBO Journal. 30:3416-29 > Full article
2010
  1. Abe N, Borson SH, Gambello MJ, Wang F and Cavalli V. (2010). Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves. J Biol Chem. 285(36):28034-43 . > Full article
  2. Tuck E, and Cavalli V. (2010). Roles of membrane trafficking in nerve repair and regeneration Commun Integr Biol. 3:209-14.  > Full article
  3. Sun F, and Cavalli V. (2010). Neuroproteomics approaches to decipher neuronal regeneration and degeneration. Mol Cell Proteomics. 9(5) 963-75. > Full article
2009
  1. Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V. (2009). Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem. 284 (50): 34628-39 > Full article
2008
  1. Abe N, Cavalli V (2008). Nerve injury signaling. Curr Opin Neurobiol.  > Full article 
2007
  1. Haghnia M, Cavalli V, Shah SB, Schimmelpfeng K, Brusch R, Yang G, Herrera C, Pilling A, Goldstein LS (2007). Dynactin Is Required for Coordinated Bidirectional Motility, but Not for Dynein Membrane Attachment. Mol Biol Cell. 18 (6): 2081-9. > Full article 
2005
  1. Cavalli V, Kujala P, Klumperman J, Goldstein LS (2005). Sunday Driver links axonal transport to damage signaling. J Cell Biol. 168: 775-87. > Full article

Featured Articles

Highlighted in in Faculty Opinions:

Popko B and Elbaz B: Faculty Opinions Recommendation of [Avraham O et al., Nat Commun 2020 11(1):4891]. In Faculty Opinions, 19 Mar 2021;>Opinion

Washington University Record Press Release: Regrowing damaged nerves hinges on shutting down key genes.   > Full article 

Wash U press release: Master gene orchestrates regeneration of damaged peripheral nerves  Full article  

Editor’s Choice Science Signaling, Programming Neuronal Regeneration, by Nancy R. Gough, November 2013 Vol. 6, Issue 302.>Full article

Nature Reviews in Neuroscience, Neural repair, Export duties for HDAC5, by Katherine Whalley, 15,4-5 (2014)  >Full article

The Scientist, Epigenetices of Regeneration by Abby Olena, February 1, 2014. >Full article

Chen L and Rolls M. (2012). EMBO Journal 31(14):3033-5 >Full article 

Nix P and Bastiani M. (2012). Neuron, 74(6), 961-963.>Full article