Feng R, Muraleedharan Saraswathy V, Mokalled MH, Cavalli V. (2023) Self-renewing macrophages in dorsal root ganglia contribute to promote nerve regeneration. PNAS. 120(7):e2215906120. doi: 10.1073/pnas.2215906120. Epub 2023 Feb 10.
2022
Avraham O, Le J, Leahy K, Li T, Zhao G, Cavalli V. (2022) Analysis of neuronal injury transcriptional response identifies CTCF and YY1 as co-operating factors regulating axon regeneration. Front Mol Neurosci. 15:967472. doi: 10.3389/fnmol.2022.967472. eCollection 2022.
Avraham O, Chamessian A, Feng R, Yang L, Halevi A, Moore A, Gereau R, Cavalli V. (2022) Profiling the molecular signature of satellite glial cells at the single cell level reveals high similarities between rodents and humans. Pain. 163(12):2348-2364. Featured publication article »
Deng P-Y, Kumar A, Cavalli V, Klyachko VA. (2022) FMRP regulates GABAa receptor channel activity to control signal integration in hippocampal granule cells. Cell Reports. 39(7):110820. doi: https://doi.org/10.1016/j.celrep.2022.110820.
Avraham O, Deng P, Maschi D, Klyachko V, Cavalli V. (2022) Disrupted association of sensory neurons with enveloping satellite glial cells in Fragile X mouse model. Frontiers in Molecular Neuroscience. 14:796070. Resources available »
2021
Deng P, Avraham O, Cavalli V, Klyachko V. (2021) Hyperexcitability of sensory neurons in Fragile X mouse model. Frontiers in Molecular Neuroscience. 14:796053.
Avraham O, Feng R, Ewan EE, Zhao G, Cavalli V. (2021) Profiling sensory neuron microenvironment after peripheral and central axon injury reveals key pathways for axon regeneration. eLife. 10:e68457 Press release » Resources available »
Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo cJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M , Gereau 4th RW, Alexander-Brett J, Cavalli V, Davidson S, Hu H , Liu Q , Kim BS. (2021) 12IL-33 signaling in sensory neurons promotes dry skin itch. J Allergy Clin Immunol. S0091-6749(21)01405-6.
Spears LD, Adak S, Dong G, Wei X, Spyropoulos G, Zhang Q, Yin L, Feng C, Hu D, Lodhi IJ, Hsu F-, Rajagopal R, Noguchi KK, Halabi CM, Brier L, Bice AR, Lananna BV, Musiek ES, Avraham O, Cavalli V, Holth JK, Holtzman DM, Wozniak DF, Culver JP, Semenkovich CF. (2021) Endothelial ether lipids link the vasculature to blood pressure, behavior, and neurodegeneration. J Lipid Res. 62:100079. doi: 10.1016/j.jlr.2021.100079.
Avraham O, Charmessian A, Feng R, Halevi AE, Moore AM, Gereau RW, Cavalli V. (2021) Profiling the molecular signature of Satellite Glial Cells at the single cell level reveals high similarities between rodent and human. >Pre-print
Pita-Thomas W, Mangetti Concalves T, Zhao G, Cavalli V (2021) Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration. Scientific Reports. (11):14924.
2020
Ewan EE, Avraham O, Carlin D, Goncalves TM, Zhao G, Cavalli V. (2020) Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism.Scientific Reports. 11:374.
Carlin D, Halevi A, Ewan EE, Moore A, and Cavalli V. (2019). Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia. eNeuro. 6(3). pii ENEURO.0168-19.
Pita-Thomas W, Mahar M, Joshi A, Gan D, Cavalli V. (2019). HDAC5 promotes optic nerve regeneration in retinal ganglion cells. Exp Neurology. 317:217-283.
Balkunde R, Foroughi L, Ewan E, Emenecker R, Cavalli V, Dixit R. (2019). Mechanism of microtubule plus-end tracking by the plant-specific SPR1 protein and its development as a versatile plus-end marker. J Biol Chem. 294(44):16374-16384. doi: 10.1074/jbc.RA119.008866. Epub 2019 Sep 16.
2018
Oh YM, Mahar M, Ewan E, Leahy K, Zhao G, Cavalli V. (2018) The epigenetic regulator UHRF1 inactivates REST and growth suppressor gene expression via DNA methylation to promote axon regeneration. PNAS. 115(52):E12417-E12426. Press release »
Carlin D, Golden JP, Mogha A, Samineni VK, Monk KR, Gereau RW 4th, Cavalli V. (2018). Deletion of Tsc2 in nociceptors reduces target innervation, ion channel expression, and sensitivity to heat. eNeuro. 5(2):ENEURO.0436-17.2018. doi: 10.1523/ENEURO.0436-17.2018. eCollection 2018 Mar-Apr.
Mahar M, Cavalli V. (2018). Intrinsic mechanisms of neuronal axon regeneration. Nature Reviews Neuroscience. 19:323–337.
Pita Thomas W, Barroso-Garcia G, Moral V, Hackett A, Cavalli V, Nieto-Diaz, M. (2017) Identification of axon growth promoters in the secretome of the deer antler velvet. Neuroscience. 340:333-344.
2017
Ban N, Siegfried CJ, Lin JB, Shui YB, Sein J, Pita-Thomas W, Sene A, Santeford A, Gordon M, Lamb R, Dong Z, Kelly SC, Cavalli V, Yoshino J, Apte RS. (2017) GDF15 is elevated in mice following retinal ganglion cell death and in glaucoma patients. JCI Insight. 2(9).
2016
Mogha A, Harty BL, Carlin D, Joseph H, Sanchez NE, Suter U, Piao X, Cavalli V, Monk KR. (2016) Gpr126/Adgrg6 has Schwann cell autonomous and non-autonomous functions in peripheral nerve injury and repair. J Neuroscience. 36(49):12351-12367.
Saito A and Cavalli V. (2016) Signaling over distances. Mol Cell Proteomics. 15:382-93.
2015
Cho Y, Shin JE, Ewan EE, Oh YM, Pita-Thomas W, Cavalli V (2015) Activating injury-responsive genes with hypoxia enhances axon regeneration through neuronal HIF-1α. Neuron. 18:720-34. Press release »
Cho Y, Park D, Cavalli V. (2015). Filamin A is required in injured axons for HDAC5 activity and axon regeneration. J Biol Chem. 290(37):22759-70.
Watt D, Dixit R, Cavalli V. (2015). JIP3 activates kinesin-1 motilty to promote axon elongation. J Biol Chem. 290(25):15512-25.
Song W*, Cho Y*, Watt D, Cavalli V. (2015) Tubulin-tyrosine ligase (TTL)-mediated increased in tyrosinated α-tubulin in injured axons is required for retrograde injury signaling and axon regeneration. J Biol Chem. 290(23):14765-75.
2014
Cho Y*, DiLiberto V*, Carlin D, Li KH, Guan S, Michaelevski I, Abe N, Burlingame A, Cavalli V. (2014) Syntaxin13 expression is regulated by mammalian target of rapamycin (mTOR) in injured neurons to promote axon regeneration. J Biol Chem. 289(22):15820-15832.
Cho Y and Cavalli V. (2014) HDAC signaling in neuronal development and axon regeneration. Curr Opin Neurobiol. 27:188-126.
Shin JE, Miller BR, Babetto E, Cho Y, Sasaki Y, Qayuma S, Russlera EV, Cavalli V, Milbrandt J, DiAntonio A. (2012) SCG10 is a JNK target in the axonal degeneration pathway. PNAS. 109(52):E3696-705.
Shin JE, Cho Y, Beirowski B, Milbrandt J, Cavalli V, DiAntonio A. (2012) Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration. Neuron. 74(6):1015-1022. Preview highlight in Neuron »
Di Liberto V and Cavalli V. (2012) Ready, STAT, go: transcription factors on the move. EMBO Journal. 31(6):1331-3.
2011
Sun F, Zhu Z, Dixit R, Cavalli V. (2011). Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility. EMBO Journal. 30:3416-29.
2010
Abe N, Borson SH, Gambello MJ, Wang F, Cavalli V. (2010) Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves. J Biol Chem. 285(36):28034-43.
Tuck E and Cavalli V. (2010) Roles of membrane trafficking in nerve repair and regeneration. Commun Integr Biol. 3:209-14.
Sun F and Cavalli V. (2010) Neuroproteomics approaches to decipher neuronal regeneration and degeneration. Mol Cell Proteomics. 9(5):963-75.
2009
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V. (2009) Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem. 284(50):34628-39.
2008
Abe N, Cavalli V. (2008) Nerve injury signaling. Curr Opin Neurobiol. 18(3):276-83. doi: 10.1016/j.conb.2008.06.005.
2007
Haghnia M, Cavalli V, Shah SB, Schimmelpfeng K, Brusch R, Yang G, Herrera C, Pilling A, Goldstein LS (2007). Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell. 18(6):2081-9.