Current craniotomies are primarily performed via manual drilling, which requires several months of training, is time consuming to perform, leads to inconsistent craniotomies, and if done improperly can result in cerebral bleeding and inflammation that negatively impacts the quality of subsequent PAM images. A device that can automate the craniotomy process would allow for faster procedure times and more consistent outcomes. The device should be able to complete a craniotomy in under 15 minutes and require less than 1 month of training to use unassisted. The device should achieve a level of accuracy and precision that minimizes cerebral bleeding and inflammation. The device must also be constructed out of materials suitable for a laboratory setting. The project will be completed upon delivery of such a device, along with the associated control software, mechanical drawings, circuit diagrams, and user manuals, that allows the members of the Hu Lab to perform automated craniotomies when conducting their experiments.