IDDRC Flagship Project Pilot Funding

The Washington University Intellectual and Developmental Disability Research Center (IDDRC@WUSTL) is now accepting proposals for an investigator initiated R01 to embed within its 2025 competing renewal application. The funding mechanism for IDDRCs requires an embedded R01 project, and the inclusion of a compelling project which utilizes and represents the institutional strengths of the IDDRC can have a significant impact on the scoring of the overall renewal. To support the development of such R01 applications, we are offering a year of competitive pilot support for ~3 proposals to generate key preliminary data and build infrastructure to develop the embedded R01s. The deadline for submitting a proposal is May 15, 2023. See full RFA (attached) and the IDDRC website for additional details.

Projects may be awarded up to $45,000 this year from the following sources:

·       $25,000 from the IDDRC@WUSTL Engelhardt Family Foundation Innovation (EF2I) Fund

·       $15,000 from the Mallinckrodt Institute of Radiology (MIR) Pilot Studies Program, which provides funds for scan time in MIR facilities

·       $5,000 from the Institute for Clinical and Translational Sciences (ICTS) Just In Time (JIT) Core Usage Program, which provides vouchers for use of ICTS Cores; the IDDRC@WUSTL is an ICTS-affiliated Core

Contact Susan Maloney (maloneys@wustl.edu) for consultation on study design and applications involving the Animal Behavior Subunit.

Applicants should submit the following:

  • Principal investigator(s) and proposed project title
  • Specific Aims page (NIH-format) 
  • 300-word statement describing how the investigator would use immediate pilot funding to generate

For up to 3 of the most compelling proposals, the respective investigators will be invited to develop a full R01 proposal (with the assistance of leading scientists within the IDDRC@WUSTL) and receive up to $45,000 in immediate pilot funding/support.   The expectation is that a complete R01 application will be prepared by September 15, 2024. From these applications, one finalist will be selected for integration and inclusion in the 2025 IDDRC@WUSTL renewal application.  It is anticipated that all three invited R01s, whether or not selected for final inclusion in the renewal application, would be eligible for separate submission as stand-alone grants, with timing of submission at the discretion of the investigators.

Specific stipulations of the proposed R01 are as follows:

  1. The proposal must be a NEW study, must critically relate to developmental disabilities research, and include at least one element of translational relevance (relating to risk assessment, outcomes assessment, or intervention).

2. The proposal must substantively utilize at least one Scientific Core Facility of the IDDRC@WUSTL.  Additional information on these core facilities can be found on the IDDRC@WUSTL website.  Core services can also be potentially expanded to suit the needs of the embedded project, especially if this builds key new capacities for the IDDRC.  Discuss any such innovations with core directors.

3. The proposal must fit within a modular R01 budget for direct costs acquired through this mechanism, however can capitalize upon available funding from other sources.

4. The proposal must address one or more of the four research themes of the IDDRC@WUSTL:

Applications should be submitted as a pdf attachment to the IDDRC@WUSTL email: iddrc@email.wustl.edu (cc: abbaccha@wustl.edu) with “IDDRC R01 Specific Aims Letter of Intent” in the subject line.

DEADLINES and Important Dates:

  • Specific Aims Page, plus 300-word pilot request addendum – May 15, 2023 (DEADLINE)
  • Up to 3 Investigators selected to submit full proposals and awarded Pilot Funds – July 1, 2023
  • Draft R01s (Aims, Research Strategy, Budget) from all 3 investigators due – July 1, 2024
  • IDDRC Flagship project selected by IDDRC leadership – Aug 1, 2024
  • Selected Investigators’ full proposals due – September 15, 2024
  • Anticipated NIH P50 IDDRC Grant Application Due Date – January 25, 2025     ** Dates are subject to change based on the issuance of the RFA from NICHD.

Additional guidance for the development of specific aims for this proposal can be provided by IDDRC@WUSTL scientific liaisons Drs. Tychele Turner (tychele@wustl.edu) and Jeffrey Neil (neil@wustl.edu),  well as Center leadership (core and unit directors).  Administrative Support:  Program Manager, Anna Abbacchi (abbaccha@wustl.edu), Grants Specialist, Diane Robison (robisond@wustl.edu), and Daniel Gray (drgray@wustl.edu).


The IDDRC ABS is an affiliated core of the ICTS/Hope Center Just-In-Time (JIT) Core Usage Funding Program. Apply here for funding for your project.

Please follow these instructions when applying for ICTS JIT funding for the IDDRC ABS.